ADAM17 Antibody
Source: Rabbit mAb Catalog No. : CY6698
ADAM17 Antibody (CY6698)
UniProt:P78536
Application:WB,ICC/IF,IP,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY6698
数据表
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UniProt
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Mol Weight100kDa
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Alternative NamesCD156b; ADAM17; CSVP; TACE;
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ImmunogenA synthesized peptide derived from human ADAM17
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionTACE is responsible for the shedding of EGFR ligands such as amphiregulin and TNF-α. Some tumors have hyperactivated EGFR due to upregulated TNF-α production and upregulated TACE, making TACE a potential target for drug development. TACE activates Notch in a ligand-independent manner and has been shown to play a role in the development of the Drosophila nervous system.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,ICC/IF,IP,FC
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Recommended dilutionWB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:100
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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
Western blot analysis of ADAM17 expression in Hela cell lysate. -
Immunofluorescent analysis of Hela cells, using ADAM17 Antibody. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Immunofluorescent analysis using the Antibody at 1:200 dilution.
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