Granzyme B Antibody
Source: Rabbit mAb Catalog No. : CY6795
Granzyme B Antibody (CY6795)
UniProt:P10144
Application:IHC,ICC/IF,IP
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY6795
数据表
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UniProt
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Mol Weight38kDa
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Alternative NamesGranzyme B; Cathepsin G-like 1; CTSGL1; Lymphocyte protease; Fragmentin-2; Granzyme-2; Human lymphocyte protein; SECT; GZMB; CGL1; CSPB; CTLA1, GRB;
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ImmunogenA synthesized peptide derived from human Granzyme B
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThis enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Applications
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ReactivityHuman
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ApplicationIHC,ICC/IF,IP
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Recommended dilutionIHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
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Immunohistochemical analysis of paraffin-embedded human T cell lymphoma, using Granzyme B Antibody.
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