Axin2 Antibody
Source: Rabbit mAb Catalog No. : CY6803
Axin2 Antibody (CY6803)
UniProt:Q9Y2T1
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY6803
数据表
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UniProt
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Mol Weight94kDa
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Alternative NamesAxil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin;
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ImmunogenA synthesized peptide derived from human Axin2
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionAxin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
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Western blot analysis of Axin2 expression in (1) SW480 cell lysate; (2) PC-12 cell lysate. -
Immunofluorescent analysis using the Antibody at 1:25 dilution.
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