PARP Antibody
Source: Rabbit mAb Catalog No. : CY6850
PARP Antibody (CY6850)
UniProt:P09874
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（2）
http://www.abways.cn/showproduct.asp?cid=CY6850
数据表
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UniProt
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Mol Weight113,89kDa
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Alternative NamesPPOL; ADPRT; ADPRT1; pADPRT-1; PARP; PARP-1;
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ImmunogenA synthesized peptide derived from human PARP
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionInvolved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:500~1:1000 IHC 1:100~1:500 ICC/IF 1:50~1:200
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All lanes use the Antibody at 1:6K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:6K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
Immunohistochemical analysis of paraffin-embedded Rat ovary, using the Antibody at 1:300 dilution. -
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer, using the Antibody at 1:150 dilution. -
Immunohistochemical analysis of paraffin-embedded Human pituitary tumor, using the Antibody at 1:500 dilution. -
Immunohistochemical analysis of paraffin-embedded Human small cell lung cancer , using the Antibody at 1:500 dilution. -
Immunohistochemical analysis of paraffin-embedded Mouse spleen, using the Antibody at 1:300 dilution. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Western blot analysis of PARP expression in (1) HeLa cell lysate; (2) HeLa cell lysate treated with staurosporine. -
Immunohistochemical analysis of paraffin-embedded mouse testis, using PARP Antibody. -
Immunofluorescent analysis of Hela cells, using PARP Antibody .
引用文献（2条）
Repurposing sertraline sensitizes non–small cell lung cancer cells to erlotinib by inducing autophagy.-JCI insight
Napabucasin, a novel inhibitor of STAT3, inhibits growth and synergises with doxorubicin in diffuse large B-cell lymphoma-Cancer Letters (CANCER LETT)
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