Leptin Receptor Antibody
Source: Rabbit mAb Catalog No. : CY6854
Leptin Receptor Antibody (CY6854)
UniProt:P48357
Application:WB
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY6854
数据表
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UniProt
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Mol Weight150kDa
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Alternative NamesLeptin receptor; LEP-R; HuB219 OB receptor; OB-R; CD295; LEPR; DB; OBR;
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ImmunogenA synthesized peptide derived from human Leptin Receptor
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionOn ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones (By similarity).
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB
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Recommended dilutionWB 1:500~1:2000
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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
Western blot analysis of Leptin Receptor expression in SH-SY5Y cell lysate. -
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
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