LXR alpha Antibody
Source: Rabbit mAb Catalog No. : CY6866
LXR alpha Antibody (CY6866)
UniProt:Q13133
Application:WB,ICC/IF,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY6866
数据表
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UniProt
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Mol Weight50kDa
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Alternative NamesLiver X receptor alpha; LXR a; LXRA; NR1H3; RLD1;
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ImmunogenA synthesized peptide derived from human LXR alpha
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionOrphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,ICC/IF,FC
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Recommended dilutionWB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50
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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
Western blot analysis of LXR alpha expression in Jurkat cell lysate. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Immunofluorescent analysis using the Antibody at 1:150 dilution.
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