Drosha Antibody
Source: Rabbit mAb Catalog No. : CY6870
Drosha Antibody (CY6870)
UniProt:Q9NRR4
Application:WB,IHC,ICC/IF,FC
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY6870
数据表
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UniProt
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Mol Weight159kDa
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Alternative NamesRibonuclease 3 (EC:3.1.26.3); Protein Drosha; Ribonuclease III; RNase III; p241; DROSHA; RN3; RNASE3L; RNASEN;
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ImmunogenA synthesized peptide derived from human Drosha
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionDrosha was identified as a nuclear RNase III that catalyzes the initial step of microRNA (miRNA) processing. This enzyme processes the long primary transcript pri-miRNAs into stem-looped pre-miRNAs. Interference of Drosha results in the increase of pri-miRNAs and the decrease of pre-miRNAs. Drosha exists in a multiprotein complex called Microprocessor along with other components such as DGCR8. Drosha, along with DGCR8, is necessary for miRNA biogenesis.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50
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Western blot analysis of Drosha expression in 293 cell lysate. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:2W dilution for 1 hour at room temperature.
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