BACE1 Antibody
Source: Rabbit mAb Catalog No. : CY6880
BACE1 Antibody (CY6880)
UniProt:P56817
Application:WB,IP
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY6880
数据表
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UniProt
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Mol Weight70kDa
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Alternative NamesBeta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Memapsin-2; BACE1; BACE;
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ImmunogenA synthesized peptide derived from human BACE1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionResponsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IP
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Recommended dilutionWB 1:500~1:2000 IP 1:40
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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
Western blot analysis of BACE1 expression in SH-SY5Y cell lysate.
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