P27695

36kDa

DNA-(apurinic or apyrimidinic site) lyase; APEX nuclease; APEN; AP endonuclease 1; APE-1; APEX1; APE; APE1; APEX; APX; HAP1; REF1;

A synthesized peptide derived from human APE1

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Affinity-chromatography

Rabbit IgG

Monoclonal

Ape1 initiates the repair of abasic sites and is essential for the base excision repair (BER) pathway. Repair activities of Ape1 are stimulated by interaction with XRCC1, another essential protein in BER. Ape1 functions as a redox factor that maintains transcription factors in an active, reduced state but can also function in a redox-independent manner as a transcriptional cofactor to control different cellular fates such as apoptosis, proliferation and differentiation.

Human,Mouse,Rat

WB,IHC

WB 1:1000~1:5000 IHC 1:50~1:200