PHD2 / prolyl hydroxylase Antibody
Source: Rabbit mAb Catalog No. : CY7001
PHD2 / prolyl hydroxylase Antibody (CY7001)
UniProt:Q9GZT9
Application:WB,IP
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY7001
数据表
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UniProt
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Mol Weight46kDa
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Alternative NamesEGLN1; C1orf12; ECYT3; HIFPH2; HPH2; PHD2; SM-20; SM20; ZMYND6;
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ImmunogenA synthesized peptide derived from human PHD2 / prolyl hydroxylase
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionCatalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
Applications
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ReactivityHuman
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ApplicationWB,IP
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Recommended dilutionWB 1:500~1:2000 IP 1:50
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All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature. -
Western blot analysis of PHD2 / prolyl hydroxylase expression in SH-SY5Y cell lysate.
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