FADD Antibody
Source: Rabbit mAb Catalog No. : CY7129
FADD Antibody (CY7129)
UniProt:Q61160(mouse)(human:Q13158)
Application:WB,IHC,FC
Reactivity:Mouse
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY7129
数据表
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UniProt
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Mol Weight28kDa
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Alternative NamesFADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1;
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ImmunogenA synthesized peptide derived from human FADD
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionApoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Applications
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ReactivityMouse
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ApplicationWB,IHC,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 FC 1:50
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Western blot analysis of FADD expression in Raw264.7 cell lysate.
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