Securin Antibody
Source: Rabbit mAb Catalog No. : CY7156
Securin Antibody (CY7156)
UniProt:O95997/Q6IAL9
Application:WB,IHC,ICC/IF,IP,FC
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY7156
数据表
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UniProt
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Mol Weight28kDa
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Alternative NamesCut2; EAP1; hPTTG; Pds1; PTTG; PTTG1; Pttg3; Securin; TUTR1;
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ImmunogenA synthesized peptide derived from human Securin
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionRegulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF,IP,FC
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Recommended dilutionWB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 FC 1:50
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Western blot analysis of Securin expression in HeLa cell lysate.
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