Phospho-IKB alpha (S36) Antibody
Source: Rabbit mAb Catalog No. : CY7246
Phospho-IKB alpha (S36) Antibody (CY7246)
UniProt:P25963
Application:WB,FC
Reactivity:Human,Mouse
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY7246
数据表
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UniProt
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Mol Weight39kDa
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Alternative NamesI kappa B alpha; IkappaBalpha; IkB-alpha; IKBA; IKBalpha; MAD3; NF kappa B inhibitor alpha; NFKBI; NFKBIA;
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ImmunogenA synthesized peptide derived from human Phospho-IKB alpha (S36)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionInhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Applications
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ReactivityHuman,Mouse
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ApplicationWB,FC
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Recommended dilutionWB 1:500~1:2000 FC 1:50
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Western blot analysis of Phospho-IKB alpha (S36) expression in HeLa cell lysate treated with Calyculin A. -
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
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