phospho-Phospholipase C gamma 1/PLC-gamma-1 (Y1253)
Source: Rabbit mAb Catalog No. : CY8175
phospho-Phospholipase C gamma 1/PLC-gamma-1 (Y1253) (CY8175)
UniProt:P19174
Application:WB
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY8175
数据表
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UniProt
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Mol Weight149 kDa
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Alternative NamesPLC-148; PLC-II; PLC-gamma1; PLC1; PLCG-1; Phospholipase C-gamma-1;
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ImmunogenA synthesized peptide derived from human phospho-Phospholipase C gamma 1/PLC-gamma-1 (Y1253)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionPlays a role in actin reorganization and cell migration. The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.
Applications
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ReactivityHuman
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ApplicationWB
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Recommended dilutionWB 1:500~1:2000
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Western blot analysis of phospho-Phospholipase C gamma 1/PLC-gamma-1 (Y1253) expression in Jurkat treated with Pervanadate lysate.
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