CRM1 Antibody
Source: Rabbit mAb Catalog No. : CY8203
CRM1 Antibody (CY8203)
UniProt:O14980
Application:WB,IHC,ICC/IF,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY8203
数据表
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UniProt
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Mol Weight110kDa
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Alternative NamesCRM 1; emb; Exp1; Exportin1; XPO 1;
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ImmunogenA synthesized peptide derived from human CRM1
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionMediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:100
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All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
Western blot analysis of CRM1 expression in HeLa cell lysate.
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