Nicastrin Antibody
Source: Rabbit mAb Catalog No. : CY8349
Nicastrin Antibody (CY8349)
UniProt:Q92542
Application:WB,ICC/IF
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY8349
数据表
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UniProt
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Mol Weight120/140kDa
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Alternative NamesAPH2; Ncstn; NCT; Nicastrin;
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ImmunogenA synthesized peptide derived from human Nicastrin
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionEssential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
Applications
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ReactivityHuman
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ApplicationWB,ICC/IF
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Recommended dilutionWB 1:500~1:2000 ICC/IF 1:50~1:200
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Western blot analysis of Nicastrin expression in A431 cell lysate.
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