CRKII Antibody
Source: Rabbit mAb Catalog No. : CY8508
CRKII Antibody (CY8508)
UniProt:P46108
Application:WB,ICC/IF,IP,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY8508
数据表
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UniProt
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Mol Weight38kDa
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Alternative NamesCRK; CRKII; p38;
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ImmunogenA synthesized peptide derived from human CRKII
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionThe Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,ICC/IF,IP,FC
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Recommended dilutionWB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:100
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Western blot analysis of CRKII expression in K562 cell lysate. -
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
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