P00533

175kDa

kinase EGFR; ERBB1; Epidermal growth factor receptor precursor;

A synthesized peptide derived from human EGFR Full-length sequence 1210aa around the Leucine 858 mutation Arginine

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Affinity-chromatography

Rabbit IgG

Monoclonal

EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

Human

WB,IHC,ICC/IF

WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:100