Phospho-Tuberin (T1462) Antibody
Source: Rabbit mAb Catalog No. : CY8947
Phospho-Tuberin (T1462) Antibody (CY8947)
UniProt:P49815
Application:WB,IHC
Reactivity:Human,Mouse
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY8947
数据表
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UniProt
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Mol Weight200kDa
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Alternative NamesLAM; PPP1R160; Protein phosphatase 1, regulatory subunit 160; tsc2; TSC4; TSC4, formerly; Tuberin; Tuberous sclerosis 2;
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ImmunogenA synthesized peptide derived from human Phospho-Tuberin (T1462)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionIn complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1.
Applications
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ReactivityHuman,Mouse
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ApplicationWB,IHC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200
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