Phospho-Phospho-PKR (T451) Antibody
Source: Rabbit mAb Catalog No. : CY9236
Phospho-Phospho-PKR (T451) Antibody (CY9236)
UniProt:P19525
Application:WB
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY9236
数据表
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UniProt
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Mol Weight68kDa
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Alternative NamesEIF2AK1; EIF2AK2; p68 kinase; PKR; PPP1R83; PRKR; Protein kinase RNA activated;
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ImmunogenA synthesized peptide derived from human Phospho-Phospho-PKR (T451)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionFollowing activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.
Applications
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ReactivityHuman
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ApplicationWB
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Recommended dilutionWB 1:500~1:2000
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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
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