Phospho-Chk2 (S33 + S35) Antibody
Source: Rabbit mAb Catalog No. : CY9792
Phospho-Chk2 (S33 + S35) Antibody (CY9792)
UniProt:O96017
Application:WB
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY9792
数据表
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UniProt
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Mol Weight65kDa
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Alternative NamesCds1; Checkpoint kinase 2; Chek2; hCds1; LFS2; RAD53; Serine/threonine protein kinase Chk2;
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ImmunogenA synthesized peptide derived from human Phospho-Chk2 (S33 + S35)
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionRegulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.
Applications
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ReactivityHuman
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ApplicationWB
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Recommended dilutionWB 1:500~1:2000
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All lanes use the Antibody at 1:1k dilution for 1 hour at room temperature.
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