Osteoprotegerin Antibody
Source: Rabbit mAb Catalog No. : DY1305
Osteoprotegerin Antibody (DY1305)
UniProt:O00300
Application:IHC,ICC/IF
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=DY1305
数据表
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UniProt
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Mol WeightkDa
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Alternative NamesFormer Catalog No. CY10305; OCIF; OPG; Osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; TNFRSF11B; TR1;
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ImmunogenA synthesized peptide derived from human Osteoprotegerin
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionActs as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.
Applications
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ReactivityHuman
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ApplicationIHC,ICC/IF
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Recommended dilutionIHC 1:50~1:200 ICC/IF 1:50~1:200
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