SOCS7 Antibody
Source: Rabbit mAb Catalog No. : DY1428
SOCS7 Antibody (DY1428)
UniProt:O14512
Application:WB,IHC
Reactivity:Human
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=DY1428
数据表
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UniProt
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Mol Weight63kDa
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Alternative NamesFormer Catalog No. CY10428; Ash and phospholipase C gamma-binding protein; NAP4; Nck; Nck Ash and phospholipase C binding protein; Nck associated protein 4; NCKAP4; SH2 domain containing SOCS box protein; SOCS4; SOCS6; Socs7; Suppressor of cytokine signa
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ImmunogenA synthesized peptide derived from human SOCS7
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionRegulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.
Applications
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ReactivityHuman
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ApplicationWB,IHC
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200
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Western blot analysis of SOCS7 expression in HeLa cell lysate. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.
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