Fibronectin (1E2) Mouse mAb
Source: Mouse mAb Catalog No. : AB3451
Fibronectin (1E2) Mouse mAb (AB3451)
UniProt:P02751
Application:WB,IHC,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3451
数据表
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UniProt
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Mol Weight285kDa
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Alternative NamesCIG, Cold insoluble globulin, fibronectin 1, FN, fN1, FNZ, GFND, GFND2, UgI-Y3
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ImmunogenSynthetic Peptide of Fibronectin
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionSwiss-Prot Acc.P02751.Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.SitesFeature keyPosition(s)Description
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB: 1/500-1/1000 IHC: 1/50-1/100 ICC/IF: 1/50-1/200
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Western blot analysis of extracts from MCF7 and Hela cell lysates using Fibronectin Mouse mAb (1:1000 diluted).Predicted band size:285KDa.Observed band size:285KDa. -
Immunohistochemistry of Fibronectin in paraffin-embedded Human kidney using Fibronectin Mouse mAb diluted at 1:100.
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