CD41 (9G4) Mouse mAb_单克隆抗体-上海泊湾生物技术有限公司

CD41 (9G4) Mouse mAb

Source: Mouse mAb Catalog No. : AB3527

CD41 (9G4) Mouse mAb (AB3527)
UniProt:P08514
Application:IHC
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=AB3527

数据表

UniProt

P08514
Mol Weight

kDa
Alternative Names

ITGA2B; GP2B; ITGAB; Integrin alpha-IIb; GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD41
Immunogen

Synthetic Peptide of CD41
Storage

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Purification

Affinity-chromatography
Isotype

Mouse IgG1
Clonality

Monoclonal
Description

Swiss-Prot Acc.P08514.Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.RegionsFeature keyPosition(s)Description

Applications

Immunohistochemistry analysis of paraffinembedded Humanbreastcancer tissue using Integrin alpha Iib (9G4) antibody.Sodium citrate pH 6.0 was used for antigen retrieval.Negative control was used by secondary antibody only.
Immunohistochemical analysis of paraffinembedded human tonsils using Integrin alpha Iib (9G4) antibody.