FoxO3a Antibody
Source: Rabbit mAb Catalog No. : CY5079
FoxO3a Antibody (CY5079)
UniProt:O43524
Application:WB,IHC,ICC/IF
Reactivity:Human
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5079
数据表
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UniProt
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Mol Weight90kDa
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Alternative NamesForkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3; FKHRL1; FOXO3A
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ImmunogenA synthesized peptide derived from human FoxO3a
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionFoxO3a is a transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Applications
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ReactivityHuman
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ApplicationWB,IHC,ICC/IF
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Recommended dilutionWB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
Western blot analysis of FoxO3a in (1) Jurkat cell lysate; (2) SH-SY5Y cell lysate. -
Immunohistochemical analysis of paraffin-embedded human bladder carcinoma, using FoxO3a Antibody. -
Immunofluorescent analysis of Hela cells, using FoxO3a Antibody . -
LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway. -Journal of Experimental & Clinical Cancer Research
引用文献（1条）
LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway.-Journal of Experimental & Clinical Cancer Research
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