Bad Antibody
Source: Rabbit mAb Catalog No. : CY5366
Bad Antibody (CY5366)
UniProt:Q92934
Application:WB,IHC,ICC/IF,IP,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAb
References（1）
http://www.abways.cn/showproduct.asp?cid=CY5366
数据表
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UniProt
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Mol Weight23kDa
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Alternative NamesBAD; BBC6; BCL2L8; Bcl- XL/Bcl-2 associated death promoter; Bcl-2 binding component 6; Bcl-2-like 8 protein; Bcl-xL/Bcl-2 associated death promoter;
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ImmunogenA synthesized peptide derived from human Bad
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionPromotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,IP,FC
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Recommended dilutionWB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 FC 1:50
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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature. -
Western blot analysis of BAD expression in Hela cell lysate. -
Immunohistochemical analysis of paraffin-embedded human colon cancer, using Bad Antibody. -
Immunofluorescent analysis of Hela cells, using Bad Antibody . -
Immunofluorescent analysis using the Antibody at 1:50 dilution. -
Immunofluorescent analysis using the Antibody at 1:150 dilution.
引用文献（1条）
Abnormal neuronal damage and inflammation in the hippocampus of kainic acid-induced epilepsy mice-CELL BIOCHEMISTRY AND FUNCTION (Cell Biochem Funct)
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