Dnmt3a Antibody
Source: Rabbit mAb Catalog No. : CY5533
Dnmt3a Antibody (CY5533)
UniProt:Q9Y6K1
Application:WB,IHC,ICC/IF,FC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5533
数据表
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UniProt
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Mol Weight130kDa
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Alternative NamesDNMT3A2; M.HsaIIIA; Dnmt3a; MCMT; DNA methyltransferase 3a;
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ImmunogenA synthesized peptide derived from human Dnmt3a
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionMethylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development. Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2 and DNMT3. DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,IHC,ICC/IF,FC
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Recommended dilutionWB 1:500~1:2000 IHC 1:1000~1:2000 ICC/IF 1:100~1:500 FC 1:50
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All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
Western blot analysis of Dnmt3a expression in HeLa cell lysate.
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