FoxO3a Antibody
Source: Rabbit mAb Catalog No. : CY5898
FoxO3a Antibody (CY5898)
UniProt:O43524
Application:WB,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5898
数据表
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UniProt
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Mol Weight90kDa
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Alternative NamesForkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3; FKHRL1; FOXO3A;
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ImmunogenA synthesized peptide derived from human FoxO3a
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionFoxO3a is a transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,ICC/IF
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Recommended dilutionWB 1:1000~1:2000 ICC/IF 1:50~1:200
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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature. -
Western blot analysis of FOXO3A expression in MCF-7 cell lysate. -
Immunofluorescent analysis of Hela cells, using FoxO3a Antibody. -
Immunofluorescent analysis using the Antibody at 1:25 dilution. -
All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
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